Abstract | AIM: To determine whether an association exists between plasma lipoprotein constituents and the prevalence of corneal arcus in dyslipidaemic patients. METHODS: RESULTS: The study group divided into a subgroup with arcus 37% (43) and a subgroup without arcus 63% (72). Total serum cholesterol and triglyceride levels were not associated with corneal arcus. A significant difference was found (p < 0.05) between the mean levels of LDL cholesterol ( LDL-C) in the group without arcus (5.61 +/- 1.74 mmol/l) and the group with arcus (5.96 +/- 1.71 mmol/l). The mean serum HDL-cholesterol (HDL-C) in the group with corneal arcus was 1.04 +/- 0.30 mmol/l as opposed to 1.31 +/- 0.38 mmol/l in the group without arcus (p < 0.005 for difference). The mean LDL-C : HDL-C ratio in the group without arcus was 4.28 (SD: 1.99), and 5.73 (SD: 2.09) in the group with a corneal arcus (p < 0.05). CONCLUSIONS: Low HDL-C levels, high LDL-C levels and LDL-C : HDL-C ratios > 5 have been implicated as risk factors of numerous circulatory diseases. The observations in this study suggest that the presence of corneal arcus in the dyslipidaemic patient correlates strongly with these same risk indicators.
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Authors | D Meyer, P H Liebenberg, F J Maritz |
Journal | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners
(Cardiovasc J S Afr)
2004 Jul-Aug
Vol. 15
Issue 4
Pg. 166-9; discussion 169 South Africa |
PMID | 15322572
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Arcus Senilis
(blood, epidemiology, etiology)
- Cohort Studies
- Female
- Humans
- Hyperlipidemias
(blood, complications)
- Lipoproteins
(blood)
- Male
- Middle Aged
- Prevalence
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