Abstract | PURPOSE: To determine if topical ophthalmic application of ketorolac tromethamine concentrations below 0.5% can block the biochemical and physiological processes associated with chemically induced ocular inflammation in rabbits. METHODS: RESULTS: CONCLUSIONS: Topical application of ketorolac concentrations as low as 0.01%-0.1% significantly reduce chemically induced ocular inflammation in rabbits.
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Authors | L David Waterbury, Allan J Flach |
Journal | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
(J Ocul Pharmacol Ther)
Vol. 20
Issue 4
Pg. 345-52
(Aug 2004)
ISSN: 1080-7683 [Print] United States |
PMID | 15321029
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
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Topics |
- Animals
- Aqueous Humor
(drug effects, metabolism)
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Eye
(drug effects, metabolism, pathology)
- Inflammation
(drug therapy)
- Ketorolac Tromethamine
(administration & dosage)
- Rabbits
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