| Abstract | A comprehensive study was conducted to determine the activity of tuberculous infection in 115 patients who formed 3 groups: 1) patients with primary forms of tuberculosis; 2) those who were infected with Mycobacterium tuberculosis (MBT); and 3) those who were infected with bronchopulmonary diseases. The detection of MBT DNA in the blood by polymerase chain reaction (PCR) using a highly sensitive four-primed diagnostic kit established that 80 patients with tuberculosis had positive results and their decrease as the patient had a course of tuberculostatic therapy. The fact that a third of patients from Groups 2 and 3 had highly positive results of PCR required that a preventive course of double therapy be used for 3 to 6 months. |
| Authors | L V Klochkova, O I Korol', I A Putintseva, N A Skobeleva, O A Vostriukhina |
| Journal | Problemy tuberkuleza i bolezneĭ legkikh
(Probl Tuberk Bolezn Legk)
Issue 6
Pg. 49-51
( 2004)
ISSN: 1728-2993 Russia |
| Vernacular Title | Ispol'zovanie polimeraznoĭ tsepnoĭ reaktsii dlia diagnostiki tuberkuleza u deteĭ s patologieĭ bronkholegochnoĭ sistemy. |
| PMID | 15315134
(Publication Type: English Abstract, Journal Article)
|
| Topics |
- Adolescent
- Bronchi
(physiopathology)
- Child
- Diagnosis, Differential
- Humans
- Lung
(physiopathology)
- Polymerase Chain Reaction
(methods)
- Tuberculosis, Pulmonary
(diagnosis, physiopathology)
|
