[Changes in the cardiac hemodynamics and coronary blood flow in acute myocardial infarction due to perftoran].

Abstract

One hundred and twenty patients with acute myocardium infarction, who were receiving perftoran, were analyzed within the case study. The microcirculation condition was determined by biomicroscopy of the eye conjunctiva capillaries. Changes in capillaries were evaluated by the Ditzel classification. Hemostasis was evaluated by coalugram. The condition of the myocardium was examined by electrocardiography and Echo-cardiography. The contractive ability of the myocardium was assessed by a shortening degree of the anterior-posterior size and by the ejection fraction. According to the study results, the administration of perftoran increased the number of functioning capillaries, decreased the venous congestion and reduced the diameter of arterioles and venules. Hypercoagulation was significantly decreasing. The general evaluation of the contractive ability of myocardium was satisfactory in all patients.

• Authors: O M Aliev
• Journal: Anesteziologiia i reanimatologiia (Anesteziol Reanimatol) 2004 May-Jun Issue 3 Pg. 62-3 ISSN: 0201-7563 [Print] Russia (Federation)
• Vernacular Title: Izmemeniia serdechnoĭ gemodinamiki i koronarnogo krovotoka pri ostrom infarkte miokarda pod vliianiem perforana.
• PMID: 15314866 (Publication Type: English Abstract, Journal Article)

Chemical References

• Fluorocarbons
• perftoran

Topics

• Adult
• Aged
• Combined Modality Therapy
• Coronary Circulation (drug effects)
• Coronary Vessels (drug effects)
• Female
• Fluorocarbons (pharmacology, therapeutic use)
• Heart (drug effects, physiopathology)
• Hemodynamics (drug effects)
• Humans
• Male
• Microcirculation (drug effects)
• Middle Aged
• Myocardial Infarction (drug therapy, physiopathology)