Abstract | OBJECTIVE: METHODS: RESULTS: The total effective rate in the treated group was 71.4%, that on improving peripheral insulin resistance was 76.2%, the two parameters were similar to those in the control group. In the treated group, SI, ISI were significantly improved, and TNF-alpha, ET-1 and TXB2 significantly lowered, but no change of IRR was found. CONCLUSION: Application of YYHT principle in treating patients with diabetes mellitus type 2 of secondary failure to sulfonylurea agents could alleviate the peripheral resistance to insulin, inhibit TNF-alpha, and protect the vascular endothelial cells.
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Authors | Ping Chen, Zhang-zhi Zhu, Jiang-ming Lang, Aisheng Wei, Fasheng Chen |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 24
Issue 7
Pg. 585-8
(Jul 2004)
ISSN: 1003-5370 [Print] China |
PMID | 15307693
(Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Drugs, Chinese Herbal
- Endothelin-1
- Hypoglycemic Agents
- Sulfonylurea Compounds
- Tumor Necrosis Factor-alpha
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Topics |
- Adult
- Aged
- Diabetes Mellitus, Type 2
(drug therapy)
- Drugs, Chinese Herbal
(therapeutic use)
- Endothelin-1
(metabolism)
- Female
- Humans
- Hypoglycemic Agents
(therapeutic use)
- Insulin Resistance
- Male
- Middle Aged
- Phytotherapy
- Sulfonylurea Compounds
(therapeutic use)
- Tumor Necrosis Factor-alpha
(metabolism)
- Yin Deficiency
(drug therapy)
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