Effect of normal-fat diets, either medium or high in protein, on body weight in overweight subjects: a randomised 1-year trial.

Abstract

BACKGROUND:

We have previously reported that a fat-reduced high-protein diet had more favourable effects on body weight loss over 6 months than a medium-protein diet.

OBJECTIVE:

To extend this observation by a further 6-12 months less stringent intervention and a 24 months follow-up.

DESIGN:

A randomised 6 months strictly controlled dietary intervention followed by 6-12 months dietary counselling period, and a subsequent 24 months follow-up, comparing an ad libitum, fat-reduced diet (30% of energy) either high in protein (25% of energy, HP) or medium in protein (12% of energy, MP).

SUBJECTS:

A total of 50 overweight and obese subjects (age: 19-55 y; BMI: 26-34 kg/m(2)).

MEASUREMENTS:

Change in body weight, body composition and blood parameters.

RESULTS:

After 6 months, the HP group (n=23) achieved a greater weight loss than the MP group (n=23) (9.4 vs 5.9 kg) (P<0.01). After 12 months, 8% had dropped out in the HP vs 28% in the MP group (P<0.07). After 12 months, the weight loss was not significantly greater among the subjects in the HP group (6.2 and 4.3 kg), but they had a 10% greater reduction in intra-abdominal adipose tissue and more in the HP group (17%) lost >10 kg than in the MP (P<0.09). At 24 months, both groups tended to maintain their 12 months weight loss, but more than 50% were lost to follow-up.

CONCLUSION:

A fat-reduced diet high in protein seems to enhance weight loss and provide a better long-term maintenance of reduced intra-abdominal fat stores.

• Authors: A Due, S Toubro, A R Skov, A Astrup
• Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity (Int J Obes Relat Metab Disord) Vol. 28 Issue 10 Pg. 1283-90 (Oct 2004) England
• PMID: 15303109 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Dietary Fats
• Dietary Proteins

Topics

• Adolescent
• Adult
• Anthropometry
• Body Composition
• Body Weight
• Dietary Fats (administration & dosage)
• Dietary Proteins (administration & dosage)
• Energy Intake
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Obesity (diet therapy, physiopathology)
• Patient Compliance
• Weight Loss