[Gastrin-secreting neuroendocrine carcinoma: two cases identified and treated surgically with a radio-guided technique].

Abstract

The authors present two cases of gastrin-producing carcinoma demonstrated by scintigraphy with In-111 pentetreotide. The possible malignant evolution of such tumours and the good results that can be achieved with surgical therapy suggest the usefulness of a radio-guided intraoperative strategy to locate the lesions and minimise invasive procedures. This approach enabled us to detect a lymph-node metastasis concealed in the adipose tissue in the first case and to exclude any other gastrin-producing tumour localisations in the second. We recommend that the radio-guided strategy should be included among the guidelines for the treatment of gastrinomas and believe that the procedure can also be used in other functioning endocrine tumours.

• Authors: Umberto Pandolfi, David Cossard, Arcangelo Pesenti Campagnoni, Ferruccio Biandrate, Marco Piccolini, Luigi Francia, Francesca Zadra, Giovanni Ambrosino, Cesare Rosa, Antonio Battaglia, Mauro Carena
• Journal: Chirurgia italiana (Chir Ital) 2004 May-Jun Vol. 56 Issue 3 Pg. 383-8 ISSN: 0009-4773 [Print] Italy
• Vernacular Title: Carcinoma neuroendocrino a secrezione gastrinica: due casi identificati e trattati chirurgicamente con tecnica radioguidata.
• PMID: 15287635 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Aged
• Duodenal Neoplasms (pathology, surgery)
• Gastrinoma (secondary, surgery)
• Humans
• Lymphatic Metastasis
• Male
• Neuroendocrine Tumors (pathology, surgery)
• Pancreatic Neoplasms (pathology, surgery)
• Radiosurgery
• Treatment Outcome