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A complete and durable clinical response to high-dose dexamethasone in a patient with scleromyxedema.

Abstract
We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associated paraproteinemia.
AuthorsKeren B Horn, Meyer A Horn, James Swan, Seema Singhal, Joan Guitart
JournalJournal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 51 Issue 2 Suppl Pg. S120-3 (Aug 2004) ISSN: 1097-6787 [Electronic] United States
PMID15280830 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Dexamethasone
Topics
  • Biopsy
  • Dexamethasone (administration & dosage)
  • Drug Administration Schedule
  • Humans
  • Male
  • Middle Aged
  • Scleroderma, Diffuse (diagnosis, drug therapy, pathology)
  • Skin (pathology)

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