Case report: combination artemether-lumefantrine and haemolytic anaemia following a malarial attack.

Abstract

A case of a patient who was admitted to hospital in Paris, France, in February 2001 with autoimmune haemolytic anaemia, probably due to artemether-lumefantrine therapy, is presented. Such a complication has previously been observed in patients receiving drugs containing aryl-amino-alcohols but never before in a patient receiving lumefantrine and may be associated with the increase in episodes of blackwater fever seen in recent years.

• Authors: Stéphane Mérat, Evelyne Lambert, Isabelle Vincenti-Rouquette, Stéphane Gidenne, Jean-Marie Rousseau, Louis Brinquin
• Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene (Trans R Soc Trop Med Hyg) 2003 Jul-Aug Vol. 97 Issue 4 Pg. 433-4 ISSN: 0035-9203 [Print] England
• PMID: 15259474 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antimalarials
• Artemisinins
• Drug Combinations
• Ethanolamines
• Fluorenes
• Sesquiterpenes
• Artemether
• Lumefantrine

Topics

• Anemia, Hemolytic, Autoimmune (chemically induced)
• Antimalarials (adverse effects)
• Artemether
• Artemisinins (adverse effects)
• Drug Combinations
• Ethanolamines (adverse effects)
• Fluorenes (adverse effects)
• Humans
• Lumefantrine
• Malaria, Falciparum (drug therapy)
• Male
• Middle Aged
• Sesquiterpenes (adverse effects)