Splenopancreatic field abnormality is not unique to trisomy 13.

Abstract

Splenopancreatic fusion is an uncommon finding, usually only seen as part of the splenopancreatic field abnormality associated with trisomy 13. It may present itself either as ectopic splenic tissue in the cauda pancreatis, as ectopic pancreatic tissue in the spleen or accessory spleen, or as fusion of the cauda pancreatis and splenic hilum. In this study, we report four unrelated congenital anomaly cases presenting trisomy 21, osteocraniostenosis syndrome, isolated congenital heart defect, and oligohydramnios sequence due to prune belly syndrome, in which fusion was observed. This demonstrates that, although it may be more common in trisomy 13, this phenomenon should not be interpreted as pathognomonic to that syndrome.

• Authors: Luiz Cesar Peres, Gustavo Henrique T de Sales Barbosa, Renata Scarpat Careta, Cristiane Miziara Nassif, João Monteiro de Pina-Neto, Liane R Giuliani, Ciro Dresch Martinhago, Israel Gomy
• Journal: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society (Pediatr Dev Pathol) Vol. 7 Issue 1 Pg. 91-4 ( 2004) ISSN: 1093-5266 [Print] United States
• PMID: 15255041 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Chromosomes, Human, Pair 13
• Down Syndrome
• Female
• Fetal Death
• Humans
• Infant, Newborn
• Male
• Pancreas (abnormalities, pathology)
• Spleen (abnormalities, pathology)
• Trisomy