HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Quality of life and therapeutic result in outpatients with schizophrenia under flupenthixol treatment].

Abstract
The objective of this phase IV surveillance study was to document the efficacy and tolerability of flupenthixol as well as the quality of life of patients suffering from schizophrenia and to gain insights into which doses were actually used in specialists outpatients care. The observational variables in this study include demographic variables, details of the diagnosis as well as concomitant diseases. Further evaluations included the assessment of CGI-Scale and subjective patient quality of live assessment using a standardised questionnaire. This questionnaire SWN-K (subjective well-being under neuroleptic treatment; short version) includes 20 items on the state of health with a six-point scale from "absolutely not" to "very strong" respectively. 66.3 % Patients were treated with the depot form of flupenthixol, the rest with oral medication with mean doses of 9.2 mg/d i. m. and 6.3 mg/d p. o. respectively. 78.8 % of patients improved on the CGI-Scale, 5.5 % had an adverse event and in 4.6 % of patients this event was related to the medication. 0.3 % of patients had a serious adverse event. The mean of SWN-K improved from 61.2 to 78.5 in the course of study. The CGI improved from 5.83 to 3.43 in the course of treatment.
AuthorsK-U Kühn, B B Quednow, H Landen, M Riedel, M Thiel
JournalFortschritte der Neurologie-Psychiatrie (Fortschr Neurol Psychiatr) Vol. 72 Issue 7 Pg. 397-403 (Jul 2004) ISSN: 0720-4299 [Print] Germany
Vernacular TitleLebensqualität und Therapieerfolg in der ambulanten Schizophrenie-Therapie mit Flupentixol: Eine Anwendungsbeobachtung.
PMID15252753 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antipsychotic Agents
  • Delayed-Action Preparations
  • Flupenthixol
Topics
  • Adult
  • Antipsychotic Agents (adverse effects, therapeutic use)
  • Delayed-Action Preparations
  • Female
  • Flupenthixol (adverse effects, therapeutic use)
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Outpatients
  • Psychiatric Status Rating Scales
  • Quality of Life
  • Schizophrenia (drug therapy)
  • Surveys and Questionnaires
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: