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Protein-losing enteropathy associated with systemic lupus erythematosus: response to cyclophosphamide.

Abstract
Protein-losing enteropathy is a rare manifestation of systemic lupus erythematosus (SLE) leading to hypoalbuminemia and anasarca. We report the case of a woman with SLE who presented chronic hypoalbuminemia diagnosed as protein-losing enteropathy associated with SLE. She was refractory to prednisone and azathioprine administration but showed good response to cyclophosphamide. The diagnosis and management of hypoalbuminemia in lupus-associated enteropathy are discussed.
AuthorsGláucio R Werner de Castro, Simone Appenzeller, Manoel B Bértolo, Lílian Tereza Lavras Costallat
JournalRheumatology international (Rheumatol Int) Vol. 25 Issue 2 Pg. 135-8 (Mar 2005) ISSN: 0172-8172 [Print] Germany
PMID15249982 (Publication Type: Journal Article)
Chemical References
  • Immunosuppressive Agents
  • Cyclophosphamide
Topics
  • Adult
  • Cyclophosphamide (therapeutic use)
  • Edema (etiology)
  • Female
  • Humans
  • Hypoalbuminemia (etiology)
  • Immunosuppressive Agents (therapeutic use)
  • Lupus Erythematosus, Systemic (complications, drug therapy)
  • Protein-Losing Enteropathies (drug therapy, etiology)
  • Remission Induction

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