Abstract |
Kosan and Roche are developing the microtubule inhibitor epothilone D (KOS-862 and NSC-703147), an analog of epothilone B for the potential treatment of cancer. Phase II trials in colorectal, metastatic breast and non-small-cell lung cancers were initiated in December 2003.
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Authors | Ada Kolman |
Journal | Current opinion in investigational drugs (London, England : 2000)
(Curr Opin Investig Drugs)
Vol. 5
Issue 6
Pg. 657-67
(Jun 2004)
ISSN: 1472-4472 [Print] England |
PMID | 15242255
(Publication Type: Journal Article, Review)
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Chemical References |
- Antineoplastic Agents
- Drugs, Investigational
- Epothilones
- desoxyepothilone B
|
Topics |
- Animals
- Antineoplastic Agents
(adverse effects, chemistry, pharmacology, therapeutic use)
- Clinical Trials, Phase I as Topic
- Clinical Trials, Phase II as Topic
- Clinical Trials, Phase III as Topic
- Drug Evaluation, Preclinical
- Drugs, Investigational
(adverse effects, chemistry, pharmacology, therapeutic use)
- Epothilones
(adverse effects, chemistry, pharmacology, therapeutic use)
- Humans
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