Osteopetrorickets.

Abstract

Rickets is a paradoxical complication of osteopetrosis resulting from the inability of the osteoclasts to maintain a normal calcium-phosphorus balance in the extracellular fluid. Detection of rickets in a child with osteopetrosis is necessary, because treatment of the rickets with vitamin D leads to improvement in activity, decrease in irritability, improvement of appetite, and protects against recurrent respiratory tract infections. If bone marrow transplantation is feasible, then for better results, rickets should be completely treated prior to the transplantation.

• Authors: Chellam Kirubakaran, Kala Ranjini, Julius X Scott, Mona Basker, Gibikote Sridhar
• Journal: Journal of tropical pediatrics (J Trop Pediatr) Vol. 50 Issue 3 Pg. 185-6 (06 2004) ISSN: 0142-6338 [Print] England
• PMID: 15233199 (Publication Type: Case Reports, Journal Article)

Chemical References

• Prednisolone
• Calcitriol

Topics

• Bone Marrow Transplantation
• Calcitriol (therapeutic use)
• Humans
• Infant
• Male
• Osteopetrosis (complications, therapy)
• Prednisolone (therapeutic use)
• Rickets (diagnosis, etiology, therapy)