Abstract | PURPOSE OF REVIEW: To document the changes in treatment paradigm for the management of dry eye. Restasis is 0.05% cyclosporine A and is the first immunomodulatory agent approved for treatment of dry eye. RECENT FINDINGS: SUMMARY:
Dry eye disease is defined as an abnormality of tear film resulting in changes in the ocular surface. These changes may be seen on ocular examination with the use of fluorescein and supravital staining techniques. Classification of dry eye disease shows two main types: aqueous deficiency and evaporative loss. There is hope that both of these types of dry eye will respond to immunomodulation therapy. Restasis shows promise as the first of these agents to be approved as therapy to treat moderate to severe dry eye disease.
|
Authors | Henry D Perry, Eric D Donnenfeld |
Journal | Current opinion in ophthalmology
(Curr Opin Ophthalmol)
Vol. 15
Issue 4
Pg. 299-304
(Aug 2004)
ISSN: 1040-8738 [Print] United States |
PMID | 15232468
(Publication Type: Journal Article, Review)
|
Topics |
- Dry Eye Syndromes
(classification, diagnosis, etiology, therapy)
- Humans
- Ophthalmology
(trends)
|