Sustained remission of treatment-resistant cutaneous T-cell lymphoma with oral bexarotene.

Abstract

Cutaneous T-cell lymphomas (CTCL) encompass a spectrum of clinical and histologic variants, characterized by malignant CD4+ T lymphocytes in the skin and visceral organs. This is a case report of a 74-year-old man with CTCL, including ulcerative lesions, resistant to multiple systemic therapies. Treatment with oral bexarotene resulted in rapid and sustained remission of both cutaneous and systemic symptoms.

• Authors: Marilyn A Mehlmauer
• Journal: Cutis (Cutis) Vol. 73 Issue 6 Pg. 417-20 (Jun 2004) ISSN: 0011-4162 [Print] United States
• PMID: 15224787 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anticarcinogenic Agents
• Tetrahydronaphthalenes
• Bexarotene

Topics

• Administration, Oral
• Aged
• Anticarcinogenic Agents (therapeutic use)
• Bexarotene
• Humans
• Male
• Mycosis Fungoides (drug therapy, pathology)
• Remission Induction
• Skin Neoplasms (drug therapy, pathology)
• Tetrahydronaphthalenes (therapeutic use)