Evaluation of Astroglide, a new vaginal lubricant: effects of length of exposure and concentration on sperm motility.

Abstract

Traditional vaginal lubricants have been shown to adversely affect sperm motility. Astroglide, a new vaginal lubricant, and K-Y Jelly were tested at varying concentrations to assess their suitability for infertility patients requiring a lubricant. The vaginal lubricants tested impaired sperm motility in a concentration-dependent but not time-dependent manner. We conclude that all traditional vaginal lubricants should be avoided in patients desiring conception. Future studies should attempt to mimic in vivo conditions and focus on concentration-dependent effects.

• Authors: G N Frishman, A A Luciano, D B Maier
• Journal: Fertility and sterility (Fertil Steril) Vol. 58 Issue 3 Pg. 630-2 (Sep 1992) ISSN: 0015-0282 [Print] United States
• PMID: 1521661 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Astroglide
• K-Y jelly
• Phosphates
• Propylene Glycols
• Vaginal Creams, Foams, and Jellies
• Water
• Cellulose
• Glycerol

Topics

• Cellulose (analogs & derivatives, pharmacology)
• Female
• Glycerol (pharmacology)
• Humans
• Male
• Phosphates (pharmacology)
• Propylene Glycols (pharmacology)
• Solubility
• Sperm Motility (drug effects)
• Time Factors
• Vagina (physiology)
• Vaginal Creams, Foams, and Jellies (pharmacology)
• Water