Abstract | AIM: MATERIAL: Patients (n=100) with nonvalvular atrial fibrillation and at least 1 risk factor of thromboembolic complications. METHODS: Transesophageal echocardiography and measurement of blood D-dimer levels were carried out before and after 1 year of acenocoumarol therapy. RESULTS: Initial prevalence of left auricular thrombosis was 75%. The use of acenocoumarol for 12 months resulted in significant reduction of frequency of left auricular thrombosis. This was associated with improvement of parameters of intraatrial hemodynamics and lowering of elevated blood D-dimer levels. Clinical-instrumental predictors of presence of left auricular thrombosis and its dynamics during therapy with acenocoumarol were also elucidated.
|
Authors | E S Kropacheva, E P Panchenko, A B Dobrovol'skiĭ, D M Attaullakhanova, E S Bykova, E V Titaeva, O Iu At'kov |
Journal | Kardiologiia
(Kardiologiia)
Vol. 44
Issue 6
Pg. 19-25
( 2004)
ISSN: 0022-9040 [Print] Russia (Federation) |
Vernacular Title | Dlitel'naia terapiia nepriamymi antikoaguliantami u bol'nykh s mertsatel'noĭ aritmieĭ bez porazheniia klapanov serdtsa (prospektivnoe nabliudenie). Chast' I. Vliianie 12-mesiachnoĭ terapii atsenokumarolom na soderzhanie D-dimera, chastotu tromboza i pokazateli gemodinamiki ushka levogo predserdiia. |
PMID | 15211343
(Publication Type: Journal Article)
|
Chemical References |
- Anticoagulants
- Acenocoumarol
|
Topics |
- Acenocoumarol
- Anticoagulants
(therapeutic use)
- Atrial Fibrillation
- Follow-Up Studies
- Hemodynamics
- Humans
- Prospective Studies
- Thrombosis
|