Successful treatment of pulmonary metastasis and local recurrence of angiosarcoma with docetaxel.

Abstract

Angiosarcoma of the face and scalp of the elderly frequently recurs locally, metastasizes early despite various treatments, and has a poor prognosis. We describe a patient who had angiosarcoma of the scalp with pulmonary metastasis. Local recurrence occurred after excision and local and arterial administration of IL-2. A weekly administration method of docetaxel was therefore selected, resulting in complete remission of the pulmonary metastasis and a partial response of the local recurrence. This favorable clinical outcome in our case suggests that docetaxel therapy may be an option for the treatment of angiosarcoma of the scalp with pulmonary metastasis.

• Authors: Rieko Isogai, Akira Kawada, Yoshinori Aragane, Tadashi Tezuka
• Journal: The Journal of dermatology (J Dermatol) Vol. 31 Issue 4 Pg. 335-41 (Apr 2004) ISSN: 0385-2407 [Print] England
• PMID: 15187330 (Publication Type: Case Reports, Journal Article)

Chemical References

• Taxoids
• Docetaxel

Topics

• Diagnosis, Differential
• Docetaxel
• Hemangiosarcoma (diagnosis, drug therapy, secondary)
• Humans
• Lung Neoplasms (diagnosis, diagnostic imaging, drug therapy, secondary)
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Neoplasm Recurrence, Local (diagnosis, drug therapy, secondary)
• Scalp
• Skin Neoplasms (diagnosis, drug therapy, pathology)
• Taxoids (administration & dosage)
• Tomography, X-Ray Computed