[Diabetes following kidney transplantation. Report of 35 cases].

Abstract

Post-transplant diabetes mellitus (PTDM) is a frequent complication of renal transplantation. It has a prevalence rate ranging from 3 to 46%. We undertook a retrospective study of 175 nondiabetic renal transplant recipients to determine the prevalence rate, clinical characteristics, and risk factors of PTDM in kidney transplant recipients in our region. Thirty five patients (20%) developed PTDM, 50% were diagnosed by 3 months post transplantation. Eight patients (22.8%) were insulin recurrent. PTDM was independent of kidney source, family history of diabetes, age, sex, incidence of acute rejection, body weight gain, steroid or cyclosporine dose, use of beta-blockers and cytomegalovirus infection. Acturial 5 years survival was 79.4% in the diabetic compared to 80.5% in the control group. Patient survival was similar in the two groups. We conclude that PTDM is frequent in our patients. No significant risk factors of PTDM were identified in this study.

• Authors: Hayet Kaaroud, Karima Khiari, Soumaya Beji, Lotfi Cherif, Nejib Ben Abdallah, Fatma Ben Moussa, Khaled Ayed, Taieb Ben Abdallah, Hedi Ben Maïz
• Journal: La Tunisie medicale (Tunis Med) Vol. 82 Issue 2 Pg. 214-8 (Feb 2004) ISSN: 0041-4131 [Print] Tunisia
• Vernacular Title: Diabète induit après transplantation rénale. A propos de 35 cas.
• PMID: 15185598 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Diabetes Mellitus (etiology)
• Female
• Humans
• Kidney Transplantation (adverse effects)
• Male
• Prevalence
• Prognosis
• Retrospective Studies
• Risk Factors
• Survival Analysis