Risk behaviours and benign prostatic hyperplasia.

Abstract

OBJECTIVE:

To identify risk factors for benign prostatic hyperplasia (BPH).

SUBJECTS AND METHODS:

Medical history data, including reported urological conditions and treatments, and risk factor data were collected from 34 694 participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, a randomized controlled trial designed to evaluate methods for the early detection of cancer.

RESULTS:

Asian men had the lowest risks (odds ratio, 95% confidence interval) for nocturia (0.7, 0.5-0.9), physician-diagnosed BPH (0.3, 0.2-0.5) and transurethral prostatectomy (TURP, 0.2, 0.1-0.6), while risks for Whites and Blacks were similar for most measures of BPH. Greater alcohol intake was associated with decreased nocturia (P trend = 0.002), BPH (P trend < 0.001) and TURP (P trend < 0.001). Current tobacco use was associated with decreased nocturia (0.8, 0.7-0.9), BPH (0.7, 0.6-0.8) and TURP (0.6, 0.4-0.8) but dose-response patterns were weak.

CONCLUSION:

Asian-Americans have the lowest risk of clinical BPH. Alcohol and possibly cigarettes are related to a lower risk for BPH.

• Authors: D Kang, G L Andriole, R C Van De Vooren, D Crawford, D Chia, D A Urban, D Reding, W-Y Huang, R B Hayes
• Journal: BJU international (BJU Int) Vol. 93 Issue 9 Pg. 1241-5 (Jun 2004) ISSN: 1464-4096 [Print] England
• PMID: 15180615 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal

Topics

• Age Distribution
• Aged
• Alcohol Drinking (adverse effects)
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects)
• Black People (ethnology)
• Humans
• Male
• Middle Aged
• Prostatic Hyperplasia (ethnology, etiology, surgery)
• Risk Factors
• Smoking (adverse effects)
• Transurethral Resection of Prostate (methods)
• Urination Disorders (etiology)
• White People (ethnology)