Abstract | BACKGROUND: PATIENTS AND METHODS: Patients with birdshot retinochoroidopathy followed at La Source Eye Centre in Lausanne, Switzerland from January 1995 to December 2002 were subdivided into three subgroups according to the duration of evolution of the disease: untreated patients with no more than one year duration of the disease (group 1, n = 6); treated patients with disease duration of 1 - 7 years duration (group 2, n = 5) and patients with disease lasting for more than 7 years (group 3, n = 4). Fluorescein and indocyanine green angiographic signs (angiographic scores given by a masked observer) were analysed in the 3 groups and compared to the "cream-coloured" fundus lesions. RESULTS: Fifteen out of the 742 patients (2.0 %) seen at La Source Eye Centre during the time period considered presented BC and were included in the study. In the "early disease group" fluorescein and ICG angiography showed more severe choroidal than retinal involvement with respective scores of 3 +/- 0.79 (ICG) and 2 +/- 1.17 (FA) while there were few depigmented fundus lesions to be seen (score 1 +/- 0.27). The choroidal involvement responded well to systemic corticosteroids +/- immunosuppressive therapy (scores in groups 2 and 3 = 1.2 and 0.75), while retinal disease was stabilised at best (scores in groups 2 and 3 = 2.2. and 2.4) and depigmented fundus lesions increased (scores in groups 2 and 3 = 2.8 and 3). CONCLUSION:
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Authors | C P Herbort, K Probst, L Cimino, V T Tran |
Journal | Klinische Monatsblatter fur Augenheilkunde
(Klin Monbl Augenheilkd)
Vol. 221
Issue 5
Pg. 351-6
(May 2004)
ISSN: 0023-2165 [Print] Germany |
PMID | 15162278
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Adrenal Cortex Hormones
- Immunosuppressive Agents
- Indocyanine Green
- Fluorescein
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Chorioretinitis
(classification, diagnosis, drug therapy)
- Disease Progression
- Female
- Fluorescein
- Fluorescein Angiography
- Follow-Up Studies
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Indocyanine Green
- Male
- Middle Aged
- Treatment Outcome
- Visual Fields
(drug effects, physiology)
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