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In vitro effects of albendazole sulfoxide and praziquantel against Taenia solium and Taenia crassiceps cysts.

Abstract
We investigated the minimum exposure times of prazicuantel (PZQ) and albendazole sulfoxide (ABZSO) required for their activities against Taenia cysts in vitro as well as the 50 and 99% effective concentrations. The results showed that although the effects of both drugs are time and concentration dependent, ABZSO acts much slower and is less potent than PZQ.
AuthorsFrancisca Palomares, Guadalupe Palencia, Rodolfo Pérez, Dinora González-Esquivel, Nelly Castro, Helgi Jung Cook
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 48 Issue 6 Pg. 2302-4 (Jun 2004) ISSN: 0066-4804 [Print] United States
PMID15155240 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Anthelmintics
  • Antiplatyhelmintic Agents
  • Praziquantel
  • Albendazole
Topics
  • Albendazole (pharmacology)
  • Animals
  • Anthelmintics (pharmacology)
  • Antiplatyhelmintic Agents (pharmacology)
  • Cysticercosis (parasitology, pathology)
  • Humans
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Praziquantel (pharmacology)
  • Swine
  • Taenia (drug effects)
  • Taenia solium (drug effects)

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