Abstract |
We investigated the minimum exposure times of prazicuantel (PZQ) and albendazole sulfoxide (ABZSO) required for their activities against Taenia cysts in vitro as well as the 50 and 99% effective concentrations. The results showed that although the effects of both drugs are time and concentration dependent, ABZSO acts much slower and is less potent than PZQ.
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Authors | Francisca Palomares, Guadalupe Palencia, Rodolfo Pérez, Dinora González-Esquivel, Nelly Castro, Helgi Jung Cook |
Journal | Antimicrobial agents and chemotherapy
(Antimicrob Agents Chemother)
Vol. 48
Issue 6
Pg. 2302-4
(Jun 2004)
ISSN: 0066-4804 [Print] United States |
PMID | 15155240
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Anthelmintics
- Antiplatyhelmintic Agents
- Praziquantel
- Albendazole
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Topics |
- Albendazole
(pharmacology)
- Animals
- Anthelmintics
(pharmacology)
- Antiplatyhelmintic Agents
(pharmacology)
- Cysticercosis
(parasitology, pathology)
- Humans
- Male
- Mice
- Mice, Inbred BALB C
- Praziquantel
(pharmacology)
- Swine
- Taenia
(drug effects)
- Taenia solium
(drug effects)
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