Propionic acidemia and zinc deficiency presenting as necrolytic migratory erythema.

Abstract

Necrolytic migratory erythema was first described in 1942 in a patient with pancreatic islet cell carcinoma. The disease can, however, have other etiologies including nutritional dermatoses. Here, we describe the clinicopathological picture of a 7-year-old female patient who presented with necrolytic migratory erythema which we believe is secondary to a rare combination of zinc deficiency and propionic acidemia.

• Authors: Ammar C Al-Rikabi, Hala I Al-Homsi
• Journal: Saudi medical journal (Saudi Med J) Vol. 25 Issue 5 Pg. 660-2 (May 2004) ISSN: 0379-5284 [Print] Saudi Arabia
• PMID: 15138538 (Publication Type: Case Reports, Journal Article)

Chemical References

• Propionates
• Zinc
• propionic acid

Topics

• Acrodermatitis (etiology, pathology)
• Biopsy
• Child
• Diagnosis, Differential
• Erythema (etiology, pathology)
• Female
• Humans
• Necrosis
• Propionates (blood)
• Skin (pathology)
• Skin Diseases, Metabolic (diagnosis, pathology)
• Stevens-Johnson Syndrome (diagnosis, pathology)
• Zinc (deficiency)