Massive pleural effusion and marked increase of CA-125.

Abstract

The tumour associated CA-125 antigen is widely used in monitoring ovarian carcinoma. In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign pleural effusion, ascites, and chronic liver disease. Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.

• Authors: S F Hussain, J Grayez, A Grigorian, J T Green
• Journal: Postgraduate medical journal (Postgrad Med J) Vol. 80 Issue 943 Pg. 300-1 (May 2004) ISSN: 0032-5473 [Print] England
• PMID: 15138325 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• CA-125 Antigen
• Diuretics

Topics

• Adult
• Anti-Bacterial Agents (therapeutic use)
• CA-125 Antigen (blood)
• Diagnosis, Differential
• Diuretics (therapeutic use)
• Drainage
• Dyspnea (etiology, therapy)
• Fatal Outcome
• Female
• Humans
• Pleural Effusion (blood, etiology)
• Respiration, Artificial