HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Antenatal diagnosis of pulmonary sequestration: a review.

Abstract
The prenatal diagnosis of pulmonary sequestration has been demonstrated in 17 published reports, including a new case report presented here. In 11 cases (65 per cent), the definitive diagnosis was not appreciated until after birth, although a fetal mass was recognized on ultrasonographic study in the antenatal period. Seventy-five per cent of cases were thoracic sequestrations, and 25 per cent were abdominal lesions. Fetal hydrops, found in 35 per cent of cases, was universally associated with stillbirth or neonatal death. Polyhydramnios, pleural effusions, mediastinal shifts, pulmonary hypoplasia, and preterm labor were not uncommon findings. The high incidence of related malformations, well described in the postnatal literature, was remarkably absent in this antepartum series. Although the perinatal outcome for abdominal lung sequestrations is reasonably good, the prognosis in cases of thoracic sequestration remains guarded. Aggressive respiratory support after birth will not salvage those infants with underlying severe pulmonary hypoplasia. Early in utero catheter drainage may provide the best treatment for the pleural effusions associated with thoracic sequestrations, although this therapy remains under investigation.
AuthorsL A Dolkart, F T Reimers, W V Helmuth, M A Porte, G Eisinger
JournalObstetrical & gynecological survey (Obstet Gynecol Surv) Vol. 47 Issue 8 Pg. 515-20 (Aug 1992) ISSN: 0029-7828 [Print] United States
PMID1513526 (Publication Type: Journal Article, Review)
Topics
  • Adult
  • Bronchopulmonary Sequestration (diagnostic imaging, pathology)
  • Female
  • Humans
  • Infant, Newborn
  • Lung (pathology)
  • Pregnancy
  • Respiratory Distress Syndrome, Newborn (pathology)
  • Ultrasonography, Prenatal

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: