A comparative study of small incision trabeculectomy avoiding Tenon's capsule vis-à-vis trabeculectomy with Mitomycin-C.

Abstract

PURPOSE:

To compare the results of small incision trabeculectomy avoiding Tenon's capsule (SIT) vis-à-vis intraoperative use of Mitomycin-C (MMC) in primary chronic angle closure glaucoma.

METHODS:

A controlled prospective study was conducted on 60 consecutive primary chronic angle closure glaucoma patients requiring glaucoma filtration surgery. Patients were divided into two groups, Group I (n = 30): those undergoing SIT and Group II (n = 30): those undergoing trabeculectomy with MMC. Patients were followed up serially for 24 months and their intraocular pressure (IOP) was monitored. Success was defined as IOP < or = 22 mm Hg with no additional anti-glaucoma medication or laser/surgical intervention. Success was also defined as a 30% reduction from the initial IOP at which optic disc cupping and/or visual field changes occurred.

RESULTS:

The final mean IOP with SIT was 16.80 +/- 4.20 mm Hg as against 17.84 +/- 3.80 mm Hg with trabeculectomy with MMC. Final success rate of 93.3% was obtained with SIT versus 90% with trabeculectomy with MMC. No major complications were seen with either procedure.

CONCLUSION:

Small incision trabeculectomy safely and effectively reduces the IOP in over 90% cases. The advantages of this procedure over trabeculectomy with MMC are its low cost, use of a small (2.5 mm) limbal incision which obviates the dissection of Tenon's capsule and absence of any major complication.

• Authors: Jaychandra Das, Pankaj Sharma, Zia Chaudhuri
• Journal: Indian journal of ophthalmology (Indian J Ophthalmol) Vol. 52 Issue 1 Pg. 23-7 (Mar 2004) ISSN: 0301-4738 [Print] India
• PMID: 15132375 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Antibiotics, Antineoplastic
• Mitomycin

Topics

• Adult
• Aged
• Antibiotics, Antineoplastic (administration & dosage)
• Combined Modality Therapy
• Female
• Glaucoma, Open-Angle (drug therapy, surgery)
• Humans
• Intraocular Pressure
• Male
• Middle Aged
• Minimally Invasive Surgical Procedures
• Mitomycin (administration & dosage)
• Prospective Studies
• Trabeculectomy (methods)
• Treatment Outcome
• Visual Acuity