Abstract |
(+-)- Salsolinol [3], a substance possibly inducing parkinsonism, was biotransformed into optically active O- and/or N-methylated salsolinols 5, 6, and 7 by several Papaveraceae plants and tissue-culture cells derived from these plants. The bioconversion of racemic salsolinol into optically active tetrahydroisoquinolines has never been shown to occur, either in animals or in plants.
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Authors | K Iwasa, M Kamigauchi, N Takao |
Journal | Journal of natural products
(J Nat Prod)
Vol. 55
Issue 4
Pg. 491-5
(Apr 1992)
ISSN: 0163-3864 [Print] United States |
PMID | 1512599
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Biotransformation
- Cells, Cultured
- Chromatography, High Pressure Liquid
- Culture Techniques
- Isoquinolines
(chemistry, metabolism)
- Magnetic Resonance Spectroscopy
- Mass Spectrometry
- Plants
(metabolism)
- Stereoisomerism
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