HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Multimodal imaging in the congenital pulmonary lymphangiectasia-congenital chylothorax-hydrops fetalis continuum.

Abstract
We report on three infants with congenital chylothorax (CC) and congenital pulmonary lymphangiectasia (CPL). CPL appears to be a characteristic pathological finding in CC. Through the use of lymphoscintigraphy and computed tomography, this study suggests that CC and CPL are strongly correlated entities and that the dysplasia of the lymphatic system results in a pulmonary lymphatic obstruction sequence. The initial microscopic dilatation of the lymph channels may lead to progressive weeping of lymphatics and, consequently, to pleural effusion. Non-Immune Hydrops Fetalis (NIHF) may be the final consequence of impaired systemic venous return and may help to explain pleural-pulmonary involvement in this generalized lymph-vessel malformation syndrome.
AuthorsC Bellini, M Mazzella, C Campisi, G Taddei, F Mosca, P Tomà, G Villa, F Boccardo, A R Sementa, R C Hennekam, G Serra
JournalLymphology (Lymphology) Vol. 37 Issue 1 Pg. 22-30 (Mar 2004) ISSN: 0024-7766 [Print] United States
PMID15109074 (Publication Type: Journal Article)
Topics
  • Abnormalities, Multiple (diagnostic imaging)
  • Chylothorax (congenital, diagnostic imaging)
  • Female
  • Humans
  • Hydrops Fetalis (diagnostic imaging)
  • Infant
  • Infant, Newborn
  • Lung Diseases (congenital, diagnostic imaging)
  • Lymphangiectasis (congenital, diagnostic imaging)
  • Lymphoscintigraphy
  • Male
  • Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: