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Amediplase. Menarini.

Abstract
Amediplase, a chimeric protein containing functional domains of both tissue plasminogen activator and pro-urokinase plasminogen activator, is under development by Menarini for the potential treatment of thrombosis. Phase III trials with amediplase were underway by June 2002.
AuthorsSheila A Doggrell
JournalCurrent opinion in investigational drugs (London, England : 2000) (Curr Opin Investig Drugs) Vol. 5 Issue 3 Pg. 344-7 (Mar 2004) ISSN: 1472-4472 [Print] England
PMID15083603 (Publication Type: Journal Article, Review)
Chemical References
  • Fibrinolytic Agents
  • amediplase
  • Tissue Plasminogen Activator
  • Urokinase-Type Plasminogen Activator
Topics
  • Animals
  • Clinical Trials, Phase I as Topic
  • Fibrinolytic Agents (chemistry, pharmacokinetics, therapeutic use)
  • Humans
  • Structure-Activity Relationship
  • Thrombosis (drug therapy)
  • Tissue Plasminogen Activator (chemistry, pharmacokinetics, therapeutic use)
  • Urokinase-Type Plasminogen Activator (chemistry, pharmacokinetics, therapeutic use)

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