Effects of hypertonic dextran in hypovolaemic shock: a prospective clinical trial.

Abstract

The aim of this paper is to report the results of prospective clinical trials of hypertonic saline dextran (HSD) in the resuscitation of hypovolaemic shock in critically injured patients. There are many types of fluids, which can be administered intravenously. Recent interest in the usage of HSD solution has confirmed that they have a place in resuscitation of a patient in shock. Heart rate and arterial pressure recovered well with HSD solution. The plasma osmolarity, sodium and potassium levels were significantly elevated in patients resuscitated with HSD. Urine output recovered rapidly and was well maintained throughout.

• Authors: Emin Kaya Alpar, Vijay Vardhan Killampalli
• Journal: Injury (Injury) Vol. 35 Issue 5 Pg. 500-6 (May 2004) ISSN: 0020-1383 [Print] Netherlands
• PMID: 15081328 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Dextrans
• Saline Solution, Hypertonic
• hypertonic saline-dextran solution
• Sodium Chloride
• Sodium
• Potassium

Topics

• Adult
• Blood Pressure
• Dextrans (therapeutic use)
• Female
• Fluid Therapy (methods)
• Heart Rate
• Humans
• Male
• Middle Aged
• Osmolar Concentration
• Potassium (blood)
• Prospective Studies
• Saline Solution, Hypertonic (therapeutic use)
• Shock (etiology, physiopathology, therapy)
• Sodium (blood)
• Sodium Chloride (therapeutic use)
• Wounds and Injuries (complications, physiopathology, therapy)