The use of botulinum toxin A for treatment of possible essential blepharospasm in a dog.

Abstract

A 3-year-old Great Dane with bilateral possible essential blepharospasm resulting in ocular complications is described. Conservative treatment was not successful and the disease was treated with local injections of botulinum toxin A into the orbicularis oculi muscle. Blepharospasm disappeared completely 5 to 6 days after injection and did not reappear until 3 to 4 months later, at which time the injection was repeated. After several treatments over a period of more than 3 years no side effects have occured. Botulinum toxin A appeared to be effective in the treatment of essential blepharospasm in this dog.

• Authors: A Meyer-Lindenberg, K M Wohlfarth, E N Switzer
• Journal: Australian veterinary journal (Aust Vet J) Vol. 81 Issue 10 Pg. 612-4 (Oct 2003) ISSN: 0005-0423 [Print] England
• PMID: 15080472 (Publication Type: Case Reports, Journal Article)

Chemical References

• Botulinum Toxins, Type A

Topics

• Animals
• Blepharospasm (diagnosis, drug therapy, veterinary)
• Botulinum Toxins, Type A (administration & dosage, therapeutic use)
• Diagnosis, Differential
• Dog Diseases (diagnosis, drug therapy, pathology)
• Dogs
• Injections, Intramuscular (veterinary)
• Male