[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].

Abstract

A comparative study of antiarrhythmic drugs was performed in 81 patients with atrial fibrillation attacks in the presence of preexcitation syndrome. The first intravenous administration of cordarone was effective in 84.06%, disopyramide--in 69%, ajmaline in 44.8, verapamil in 42.1, novocaine amide in 39.4 and ethacizin in 38.5% of the patients. The first oral administration of quinidine and kinilentin arrested 80.4% of arrhythmia attacks, disopyramide 66.7% propranolol and mexitil 37.5 and 33.3%, respectively. Prospective evolution of antiarrhythmic therapy manifested with decreased therapeutic efficacy of the drugs from 55.7 to 26.2% in the whole group during the period of 1-5 years.

• Authors: I G Fomina, V V Iankin
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 70 Issue 2 Pg. 37-40 (Feb 1992) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Prospektivnaia évoliutsiia kupiruiushcheĭ terapii pri pristupakh mertsiatel'noĭ aritmii u bol'nykh s sindromom prezhdevremennogo vozbuzhdeniia zheludochkov.
• PMID: 1507816 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• diethylamino-ethmozine
• Ajmaline
• Mexiletine
• Moricizine
• quinidine bisulfate
• Propranolol
• Verapamil
• Disopyramide
• Quinidine
• Procainamide
• Amiodarone

Topics

• Adult
• Aged
• Aged, 80 and over
• Ajmaline (therapeutic use)
• Amiodarone (therapeutic use)
• Anti-Arrhythmia Agents (therapeutic use)
• Atrial Fibrillation (drug therapy)
• Disopyramide (therapeutic use)
• Female
• Humans
• Male
• Mexiletine (therapeutic use)
• Middle Aged
• Moricizine (analogs & derivatives, therapeutic use)
• Pre-Excitation Syndromes (complications)
• Procainamide (therapeutic use)
• Propranolol (therapeutic use)
• Quinidine (therapeutic use)
• Time Factors
• Verapamil (therapeutic use)