Kaposi varicelliform eruption associated with 0.1% tacrolimus ointment treatment in atopic blepharitis.

Abstract

OBJECTIVE:

To report the association of Kaposi varicelliform eruption (KVE) with 0.1% tacrolimus ointment treatment of atopic blepharitis in a patient with atopic dermatitis (AD).

METHOD:

We encountered KVE in a 20-year-old male patient with atopic blepharitis and AD who developed generalized herpetic lesions on his face 28 days after commencement of treatment.

RESULT:

The lesions resolved quickly with intravenous acyclovir treatment.

CONCLUSION:

Ophthalmologists should be well aware of KVE as a complication of immunosuppressive treatment in patients with atopic blepharitis.

• Authors: Minori Miyake-Kashima, Kazumi Fukagawa, Mari Tanaka, Yoji Takano, Murat Dogru, Naoko Asano-Kato, Shin-Ichi Takahashi, Hiroshi Fujishima
• Journal: Cornea (Cornea) Vol. 23 Issue 2 Pg. 190-3 (Mar 2004) ISSN: 0277-3740 [Print] United States
• PMID: 15075889 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiviral Agents
• Immunosuppressive Agents
• Ointments
• Tacrolimus
• Acyclovir

Topics

• Acyclovir (therapeutic use)
• Adult
• Antiviral Agents (therapeutic use)
• Blepharitis (drug therapy)
• Humans
• Immunosuppressive Agents (adverse effects)
• Kaposi Varicelliform Eruption (chemically induced, drug therapy)
• Male
• Ointments
• Tacrolimus (adverse effects)
• Virus Activation (drug effects)