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Alterations in the hematological profile in rat following whole body gamma radiation with and without venoruton pretreatment.

Abstract
The radioprotective effect of venoruton [O-(beta-hydroxyethyl)-rutoside] has been assessed in the hematological profile of Swiss albino male rats subjected to a single dose of 300 rads whole body gamma radiation. The results showed that the severity of the radiation-induced abnormalities in the red and white blood cells is significantly lessened by venoruton administered prior to radiation exposure.
AuthorsK C Kanwar, A Verma
JournalJournal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer (J Environ Pathol Toxicol Oncol) 1992 Jul-Aug Vol. 11 Issue 4 Pg. 235-9 ISSN: 0731-8898 [Print] United States
PMID1507075 (Publication Type: Journal Article)
Chemical References
  • Free Radical Scavengers
  • Hydroxyethylrutoside
  • Radiation-Protective Agents
  • troxerutin
Topics
  • Animals
  • Erythrocyte Count
  • Free Radical Scavengers
  • Hematocrit
  • Hematologic Tests
  • Hydroxyethylrutoside (administration & dosage, analogs & derivatives, pharmacology)
  • Leukocyte Count
  • Male
  • Radiation-Protective Agents (pharmacology)
  • Rats
  • Whole-Body Irradiation

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