Abstract |
A 55-year-old woman with severe, chronic, treatment-resistant ulcerating necrobiosis lipoidica of the shins was commenced on oral cyclosporin at a dose of 2.5 mg/kg/day. Improvement started within 1 week of commencing treatment, and the lesions healed completely over 8 months. Further ulceration occurred 3 months after discontinuing cyclosporin, with improvement on reintroduction of cyclosporin. There have been four previous case reports of healing of treatment-resistant ulcerating necrobiosis lipoidica with cyclosporin.
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Authors | Amy Stanway, Marius Rademaker, Paul Newman |
Journal | The Australasian journal of dermatology
(Australas J Dermatol)
Vol. 45
Issue 2
Pg. 119-22
(May 2004)
ISSN: 0004-8380 [Print] Australia |
PMID | 15068460
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Dermatologic Agents
- Immunosuppressive Agents
- Cyclosporine
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Topics |
- Cyclosporine
(therapeutic use)
- Dermatologic Agents
(therapeutic use)
- Female
- Follow-Up Studies
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Middle Aged
- Necrobiosis Lipoidica
(drug therapy)
- Recurrence
- Skin Ulcer
(drug therapy)
- Wound Healing
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