Abstract |
Certain constitutional translocations have been described to be associated with an increased risk of malignant diseases. We report here two patients, one with acute myeloid leukemia (AML) and another with biphenotypic acute leukemia, in whom constitutional translocations t(3;5)(p25;q22) and t(1;14)(p31;q21) were observed, respectively. To our knowledge, none of the above translocations has been previously reported.
|
Authors | Anna D Panani, Vasiliki Pappa, Sotirios A Raptis |
Journal | Annals of hematology
(Ann Hematol)
Vol. 83
Issue 3
Pg. 156-9
(Mar 2004)
ISSN: 0939-5555 [Print] Germany |
PMID | 15064864
(Publication Type: Case Reports, Journal Article)
|
Topics |
- Acute Disease
- Adult
- Chromosomes, Human, Pair 1
(genetics)
- Chromosomes, Human, Pair 3
(genetics)
- Chromosomes, Human, Pair 4
(genetics)
- Chromosomes, Human, Pair 5
(genetics)
- Humans
- In Situ Hybridization, Fluorescence
- Karyotyping
- Leukemia, Myeloid
(diagnosis, genetics, pathology)
- Male
- Middle Aged
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
(diagnosis, genetics, pathology)
- Translocation, Genetic
(genetics)
|