Familial Lassueur-Graham-Little-Piccardi syndrome.

Abstract

Lassueur-Graham-Little-Piccardi syndrome (LGLPS) is a rare lichenoid dermatosis characterized by progressive cicatricial alopecia of the scalp, loss of pubic and axillary hairs and keratosis pilaris. The syndrome is considered a form of follicular lichen planus (LP). Although the familial occurrence of LP is a well-described phenomenon, no familial case of LGLPS has ever been reported. We describe the occurrence of LGLPS in a mother and her daughter. HLA typing revealed HLA-DR1 in both patients. Topical tacrolimus was of partial benefit in the daughter.

• Authors: Gianmaria Viglizzo, Anna Verrini, Franco Rongioletti
• Journal: Dermatology (Basel, Switzerland) (Dermatology) Vol. 208 Issue 2 Pg. 142-4 ( 2004) ISSN: 1018-8665 [Print] Switzerland
• PMID: 15057005 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright 2004 S. Karger AG, Basel

Chemical References

• Immunosuppressive Agents

Topics

• Adult
• Alopecia (complications, drug therapy, genetics, pathology)
• Biopsy, Needle
• Cicatrix (pathology)
• Female
• Follow-Up Studies
• Humans
• Immunohistochemistry
• Immunosuppressive Agents (therapeutic use)
• Keratosis (complications, drug therapy, genetics, pathology)
• Lichen Planus (complications, drug therapy, genetics, pathology)
• Middle Aged
• Pedigree
• Risk Assessment
• Scalp Dermatoses (complications, drug therapy, genetics, pathology)
• Severity of Illness Index
• Syndrome
• Treatment Outcome