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Donepezil for alcohol-related dementia: a case report.

AbstractA 75-year old man with a 40-year history of alcoholism was admitted to the hospital for intoxication and inability to care for himself. He had been admitted frequently in the past for detoxification and rehabilitation. The patient had no family history of Alzheimer's disease, no history of head injury, and single-photon emission computed tomography showed no typical findings of Alzheimer's disease. His cognitive function was impaired. He was treated with donepezil for alcohol-related dementia, and 3 months later, his cognitive function had improved. More research is needed to confirm donepezil's role in treating alcohol-related dementia.
AuthorsKye Y Kim, Victoria Ke, Laurie M Adkins (Affiliation: Extended Care Psychiatry Program, Salem Veterans Affairs Medical Center, Salem, Virginia 24153, USA. kye.kim at med.va.gov)
JournalPharmacotherapy (Pharmacotherapy) Vol. 24 Issue 3 Pg. 419-21 (Mar 2004) ISSN: 0277-0008 United States
PMID15040658 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Indans
  • Piperidines
  • donepezil
  • Vitamin B 12
Topics
  • Aged
  • Alcohol-Related Disorders (complications, diagnosis, drug therapy)
  • Cognition Disorders (complications, diagnosis, drug therapy)
  • Drug Administration Schedule
  • Humans
  • Indans (therapeutic use)
  • Injections
  • Male
  • Piperidines (therapeutic use)
  • Time Factors
  • Treatment Outcome
  • Vitamin B 12 (administration & dosage, blood, therapeutic use)
  • Vitamin B 12 Deficiency (complications, diagnosis, drug therapy)