[Thrombosis caused by active rapamycin stents].

Abstract

We report the case history of a patient aged 68 years presenting with a recurrence of anterior myocardial infarction complicated by cardiogenic shock with a thrombosis of an active rapamycin stent 77 days following the angioplasty procedure. This was provoked by stopping platelet anti-aggregant treatment, a diabetic background and in the context of scheduled surgery for cancer recurrence. Recent data in the literature combined with our observations prompt the continuation of anti-aggregant bi therapy for at least 9 months after endoprosthesis insertion even if an active stent is used. In the case where surgery is envisaged, it is necessary to wait at least 6 months after the rapamycin stent revascularisation procedure. If an extra-cardiac procedure is envisaged during the angioplasty, it would be preferable to not use an active stent.

• Authors: R Aoudia-Mentfakh, F Raoux, J P Collet, M H Fléron, G Drobinski, J P Metzger, C Le Feuvre
• Journal: Archives des maladies du coeur et des vaisseaux (Arch Mal Coeur Vaiss) Vol. 97 Issue 2 Pg. 165-7 (Feb 2004) ISSN: 0003-9683 [Print] France
• Vernacular Title: Thrombose de stents actifs à la rapamycine.
• PMID: 15032417 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Sirolimus

Topics

• Aged
• Drug Delivery Systems (adverse effects)
• Female
• Humans
• Sirolimus (administration & dosage)
• Stents (adverse effects)
• Thrombosis (etiology)