Helicobacter pylori and hepatic encephalopathy.

Several extra-intestinal diseases have been associated with Helicobacter pylori infection. Hepatic encephalopathy has been linked to H. pylori infection because of the ammonia produced by the organism in the stomach. H. pylori infection is commoner in cirrhotic patients with hepatic encephalopathy than in those without. Increased ammonia levels have been observed in the gastric juice and blood more commonly in cirrhotics with H. pylori infection than in those without. Though the amount of ammonia produced by H. pylori may be too small to contribute to hepatic encephalopathy, eradication of H. pylori has been shown to improve the blood ammonia levels and hepatic encephalopathy.
AuthorsA Duseja, A Sachdev, R K Dhiman, Y K Chawla
JournalIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (Indian J Gastroenterol) Vol. 22 Suppl 2 Pg. S31-2 (Dec 2003) ISSN: 0254-8860 [Print] India
PMID15025251 (Publication Type: Journal Article, Review)
Chemical References
  • Ammonia
  • Ammonia (analysis)
  • Gastric Juice (chemistry)
  • Helicobacter Infections (complications, physiopathology)
  • Helicobacter pylori (physiology)
  • Hepatic Encephalopathy (etiology)
  • Humans
  • Hyperammonemia (etiology, microbiology, physiopathology)
  • Liver Cirrhosis (etiology)
  • Risk Factors

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