[Postoperative results of non-penetrating trabeculectomy for primary open-angle glaucoma].

Abstract

PURPOSE:

To estimate the postoperative results of non-penetrating trabeculectomy(NPT), the success rate of postoperative intraocular pressure(IOP) and the clinical factors affecting postoperative IOP were evaluated.

SUBJECTS AND METHODS:

32 eyes of 32 primary open-angle glaucoma(POAG) patients who underwent NPT as the first filtering surgery were enrolled in the study. We evaluated postoperative IOP using the Kaplan-Meier method, a proportional hazard model, and multiple logistic analysis.

RESULTS:

53.2% of all patients had an IOP of less than 16 mmHg without antiglaucoma medication, and 63.8% had an IOP of less than 16 mmHg with antiglaucoma medication 36 months postoperatively. The performance of Nd:YAG trabeculopuncture(YLT) was indicated as a significant factor affecting postoperative IOP by the proportional hazard model(p = 0.037). 72.2% of patients who did not undergo YLT had an IOP of less than 16 mmHg without antiglaucoma medication, and 36.5% who underwent YLT had a postoperative IOP of less than 16 mmHg. There was significant difference between the both groups(log rank test, p = 0.045). Preoperative IOP with antiglaucoma medication was indicated as a significant factor affecting performance of YLT by multiple logistic analysis.

CONCLUSION:

These results suggest that NPT may be useful to reduce the use of antiglaucoma medication in patients with POAG whose preoperative IOP is controllable with antiglaucoma medication.

• Authors: Miwako Kawashima, Yoshio Yamazaki, Kenji Mizuki, Fukuko Hayamizu, Takako Nakagami, Chizuru Tanaka
• Journal: Nippon Ganka Gakkai zasshi (Nippon Ganka Gakkai Zasshi) Vol. 108 Issue 2 Pg. 103-9 (Feb 2004) ISSN: 0029-0203 [Print] Japan
• PMID: 15022433 (Publication Type: English Abstract, Journal Article)

Chemical References

• Mitomycin

Topics

• Adult
• Female
• Glaucoma, Open-Angle (physiopathology, surgery)
• Humans
• Intraocular Pressure
• Male
• Middle Aged
• Mitomycin (administration & dosage)
• Postoperative Period
• Prognosis
• Proportional Hazards Models
• Trabeculectomy (methods)
• Treatment Outcome