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2'-Chloro-1-hydroxy-2-naphthanilide-4'-isothiocyanate--a new cestodicidal agent [1].

Abstract
2'-Chloro-1-hydroxy-2-naphthanilide-4'-isothiocyanate (4) has been synthesized as the structural analogue of yomesan (1) and was found to be active against experimental dwarf tapeworm Hymenolepis nana infection in rats at an oral dose of 7.5 mg/kg.
AuthorsH Singh, S Sharma, R N Iyer, J C Katiyar, A B Sen
JournalZeitschrift fur Naturforschung. Section C, Biosciences (Z Naturforsch C Biosci) 1978 May-Jun Vol. 33 Issue 5-6 Pg. 447-8 ISSN: 0341-0382 [Print] Germany
PMID150149 (Publication Type: Journal Article)
Chemical References
  • Anilides
  • Anticestodal Agents
Topics
  • Anilides (chemical synthesis, pharmacology)
  • Animals
  • Anticestodal Agents (chemical synthesis)
  • Hymenolepis (drug effects)
  • Male
  • Rats

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