[A case of carcinomatous lymphangitis of the lungs due to stomach cancer responding to TS-1].

Abstract

We report a case of carcinomatous lymphangitis of the lungs due to and stomach cancer showing remarkable response to TS-1. The patient was a 51-year-old man whose chest x-ray and computed tomography (CT) revealed lymphangitis, and endoscopic examination showed stomach cancer on posterior wall of stomach body. Bone marrow metastasis was suspected because platelet count was 50/microliter, and myelocytes and metamyelocytes emerged in peripheral blood. TS-1 80 mg/day was administered orally for 28 days as 1 course. After 4 courses of TS-1, chest x-ray showed remarkable improvement, and platelet count was normalized. The patient survived for 10 months after the first visit. We suggest that TS-1 is an effective therapy for carcinomatous lymphangitis of the lungs due to stomach cancer.

• Authors: Kazuyuki Akesaka, Norihiko Nakanishi, Nobuo Ueda, Tomonori Moritaka, Takushi Kitajima, Tomoya Katsuta, Keizo Furuya
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 31 Issue 2 Pg. 233-5 (Feb 2004) ISSN: 0385-0684 [Print] Japan
• PMID: 14997758 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antimetabolites, Antineoplastic
• Drug Combinations
• Pyridines
• S 1 (combination)
• Tegafur
• Oxonic Acid

Topics

• Adenocarcinoma (complications, secondary)
• Antimetabolites, Antineoplastic (therapeutic use)
• Carcinoma, Signet Ring Cell (complications, secondary)
• Drug Administration Schedule
• Drug Combinations
• Humans
• Lung Neoplasms (secondary)
• Lymphangitis (drug therapy, etiology)
• Male
• Middle Aged
• Neoplasms, Multiple Primary
• Oxonic Acid (therapeutic use)
• Pyridines (therapeutic use)
• Stomach Neoplasms (complications, pathology, secondary)
• Tegafur (therapeutic use)