HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Rocuronium for muscle relaxation in two children with Friedreich's ataxia.

Abstract
Friedreich's ataxia is a rare hereditary neurodegenerative disease caused by a defect in the gene that encodes a mitochondrial protein called frataxin. We report the use of rocuronium 0.6 mg kg(-1) in two adolescent girls with Friedreich's ataxia undergoing propofol-sufentanil-oxygen-air anaesthesia for spinal surgery. Neuromuscular transmission was monitored using acceleromyography, and onset and recovery times were recorded. The clinical duration of rocuronium was comparable to that of children without neuromuscular disease (25% recovery T(1)=44 and 24 min for patients 1 and 2 respectively).
AuthorsH J Schmitt, S Wick, T Münster
JournalBritish journal of anaesthesia (Br J Anaesth) Vol. 92 Issue 4 Pg. 592-6 (Apr 2004) ISSN: 0007-0912 [Print] England
PMID14977802 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Androstanols
  • Neuromuscular Nondepolarizing Agents
  • Rocuronium
Topics
  • Adolescent
  • Androstanols (administration & dosage)
  • Anesthesia Recovery Period
  • Anesthesia, Intravenous (methods)
  • Child
  • Female
  • Friedreich Ataxia (surgery)
  • Humans
  • Kyphosis (surgery)
  • Muscle Relaxation
  • Neuromuscular Blockade (methods)
  • Neuromuscular Nondepolarizing Agents (administration & dosage)
  • Rocuronium
  • Scoliosis (surgery)
  • Time Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: