Study of the anti-inflammatory activity of Populus tremula, Solidago virgaurea and Fraxinus excelsior.

Abstract

Aqueous/alcoholic extracts of Populus tremula, Solidago virgaurea and Fraxinus excelsior (components of Phytodolor N) were tested individually and in 3 different combinations for anti-inflammatory activity using carrageenan induced edema and/or adjuvant induced arthritis of the rat paw. The tested combinations as well as the individual extracts significantly reduced the paw edema to varying degrees and also dose dependently inhibited the arthritic paw volume. The anti-inflammatory activity of the combinations was respectively comparable to the tested doses of diclofenac.

• Authors: M el-Ghazaly, M T Khayyal, S N Okpanyi, M Arens-Corell
• Journal: Arzneimittel-Forschung (Arzneimittelforschung) Vol. 42 Issue 3 Pg. 333-6 (Mar 1992) ISSN: 0004-4172 [Print] Germany
• PMID: 1497695 (Publication Type: Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Plant Extracts
• Diclofenac
• Carrageenan

Topics

• Animals
• Anti-Inflammatory Agents (pharmacology, therapeutic use)
• Arthritis, Experimental (drug therapy)
• Carrageenan
• Diclofenac (pharmacology)
• Edema (chemically induced, drug therapy)
• Male
• Plant Extracts (pharmacology)
• Plants, Medicinal (chemistry)
• Rats
• Rats, Inbred Strains