Topical melagenine for repigmentation in twenty-two child patients with vitiligo on the scalp.

Abstract

BACKGROUND:

The purpose of this study was to evaluate the efficacy of topical melagenine for repigmentation in child patients with vitiligo on the scalp.

METHODS:

Twenty-two child patients with vitiligo on the scalp were treated with 1.2 mg/ml aqueous melagenine in combination with 20 minutes of infrared exposure twice daily.

RESULTS:

In 4 patients (18.2%), melagenine treatment in combination with infrared exposure led to complete recovery; in 6 patients (27.3%), treatment was shown to be effective; in 8 patients (36.3%), treatment led to improvements in patient condition; and only 4 patients (18.2%) showed no response after 1 - 2 treatment sessions. The general effective rate of melagenine-infrared combination treatment was 45.5% for the children with vitiligo on the scalp, and treatment was accompanied by minimal side effects.

CONCLUSION:

Melagenine may be efficacious and a safe treatment option for childhood vitiligo affecting the scalp.

• Authors: Ai-e Xu, Xiao-dong Wei
• Journal: Chinese medical journal (Chin Med J (Engl)) Vol. 117 Issue 2 Pg. 199-201 (Feb 2004) ISSN: 0366-6999 [Print] China
• PMID: 14975202 (Publication Type: Evaluation Study, Journal Article)

Chemical References

• Lipoproteins
• Melagenine

Topics

• Administration, Topical
• Adolescent
• Child
• Child, Preschool
• Female
• Humans
• Infrared Rays (therapeutic use)
• Lipoproteins (administration & dosage)
• Male
• Scalp Dermatoses (drug therapy)
• Vitiligo (drug therapy)