Acute sixth-nerve palsy after vincristine therapy.

Abstract

The chemotherapeutic effectiveness of vincristine was first reported in 1962, and with its increased use the incidence of reported neurologic side effects has also increased. We reported a case of acute sixth-nerve palsy occurring soon after administration of vincristine for acute lymphoblastic leukemia (ALL), a previously unreported side effect.

• Authors: S C Lash, C P R Williams, C S Marsh, C Crithchley, P R Hodgkins, E J Mackie
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 8 Issue 1 Pg. 67-8 (Feb 2004) ISSN: 1091-8531 [Print] United States
• PMID: 14970803 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents, Phytogenic
• Vincristine

Topics

• Abducens Nerve (drug effects)
• Abducens Nerve Diseases (chemically induced, diagnosis, therapy)
• Acute Disease
• Antineoplastic Agents, Phytogenic (adverse effects)
• Child, Preschool
• Humans
• Male
• Precursor Cell Lymphoblastic Leukemia-Lymphoma (drug therapy)
• Treatment Outcome
• Vincristine (adverse effects)
• Visual Acuity