[Photodynamic therapy for severe myopia].

Abstract

INTRODUCTION:

In the modern western world quality of life depends on the ability of reading. Our study was designed to prove the possibility of stabilization of reading acuity, central visual field and multifocal electroretinogram (mERG) after photodynamic therapy (PDT) in cases of pathologic myopia.

PATIENTS AND METHODS:

In our study 20 eyes were included. At baseline, after 6 weeks,3 months and afterwards every 3 months we investigated distance acuity, reading acuity, 10 degrees static threshold perimetry, mERG, optical coherence tomography and fluorescence angiograophy.

RESULTS:

After 1 year 85% of eyes lost less than 1.5 lines of distance acuity, the reading acuity could be stabilized in 80%, the central visual field in 60% and the ERG in 55%. Patients less than 60 years old showed better results than older patients.

DISCUSSION AND CONCLUSION:

PDT was found to be very effective because the membranes were classic without any occult parts in 100%. They were small and superficially located and the scotomas were small. There was a good correlation between functional and morphological results.

• Authors: I Krebs, S Binder, U Stolba, A Abri
• Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft (Ophthalmologe) Vol. 101 Issue 1 Pg. 25-32 (Jan 2004) ISSN: 0941-293X [Print] Germany
• Vernacular Title: Photodynamische Therapie bei hoher Myopie.
• PMID: 14872264 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Topics

• Adult
• Age Factors
• Aged
• Aged, 80 and over
• Angiography
• Electroretinography
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Myopia (classification, diagnosis, drug therapy)
• Photochemotherapy (methods)
• Pilot Projects
• Severity of Illness Index
• Tomography, Optical Coherence
• Treatment Outcome
• Vision Tests
• Visual Acuity