Overexpression of LSH1, a member of an uncharacterised gene family, causes enhanced light regulation of seedling development.

Abstract	Light regulates plant growth and development through a network of endogenous factors. By screening Arabidopsis activation-tagged lines, we isolated a dominant mutant (light-dependent short hypocotyls 1-D (lsh1-D)) that showed hypersensitive responses to continuous red (cR), far-red (cFR) and blue (cB) light and cloned the corresponding gene, LSH1. LSH1 encodes a nuclear protein of a novel gene family that has homologues in Arabidopsis and rice. The effects of the lsh1-D mutation were tested in a series of photoreceptor mutant backgrounds. The hypersensitivity to cFR and cB light conferred by lsh1-D was abolished in a phyA null background (phyA-201), and the hypersensitivity to cR and cFR light conferred by lsh1-D was much reduced in the phytochrome-chromophore synthetic mutant, hy1-1 (long hypocotyl 1). These results indicate that LSH1 is functionally dependent on phytochrome to mediate light regulation of seedling development.
Authors	Li Zhao, Miki Nakazawa, Tomoyuki Takase, Katsushi Manabe, Masatomo Kobayashi, Motoaki Seki, Kazuo Shinozaki, Minami Matsui
Journal	The Plant journal : for cell and molecular biology (Plant J) Vol. 37 Issue 5 Pg. 694-706 (Mar 2004) ISSN: 0960-7412 [Print] England
PMID	14871309 (Publication Type: Journal Article)
Chemical References	Arabidopsis Proteins DNA, Bacterial DNA, Plant LSH1 protein, Arabidopsis Nuclear Proteins T-DNA Phytochrome
Topics	Amino Acid Sequence Arabidopsis (genetics, growth & development, radiation effects) Arabidopsis Proteins (genetics, metabolism) Cloning, Molecular DNA, Bacterial (genetics) DNA, Plant (chemistry, genetics) Gene Expression Regulation, Developmental Gene Expression Regulation, Plant Hypocotyl (genetics, growth & development, radiation effects) Light Molecular Sequence Data Multigene Family Mutation Nuclear Proteins (genetics, metabolism) Phenotype Phytochrome (metabolism, radiation effects) Plant Roots (genetics, growth & development, radiation effects) Sequence Analysis, DNA Sequence Homology, Amino Acid Sequence Tagged Sites

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